A Case of Newly Onset Diabetic Ketoacidosis Following COVID-19 Infection

Fangyuan Z*, Jianfang Z and Chunlin W

Department of Pediatrics, The First Affiliated Hospital of Zhejiang University School of Medicine, China

^*Correspondance to: Zhao Fangyuan 

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Abstract:

We report a case of an 8-year-6-month-old girl who was diagnosed with COVID-19 infection more than 2 months ago. After recovery, she developed polyuria, polydipsia, polyphagia, and weight loss. Her blood glucose level was 17.5 mmol/l, and fasting C-peptide was significantly reduced. Blood ketones, urine ketones, serum anti-glutamic acid decarboxylase antibodies, and anti-insulinoma associated antigen-2 antibodies were positive, and she was diagnosed with type 1 diabetes mellitus. After fluid replacement and insulin treatment, the ketosis was corrected, and blood glucose was stabilized. COVID-19 infection may act as an initiating factor for autoimmune destruction of pancreatic beta cells, directly or indirectly impairing the function of synthesizing insulin, resulting in type 1 diabetes mellitus

Keywords:

COVID-19 infection; Children; Diabetes mellitus; Ketosis-prone diabetes mellitus

Cite the Article:

Fangyuan Z, Jianfang Z, Chunlin W. A Case of Newly Onset Diabetic Ketoacidosis Following COVID-19 Infection. Ann Clin Case Rep. 2023; 8: 2417.