Ann Clin Case Rep | Volume 8, Issue 1 | Case Report | Open Access

A Case Report of Creutzfeldt-Jakob Disease after mRNA COVID-19 Vaccine

Karabudak S1*, Kurtoğlu AV1, Uslu F1 and Gürsoy AE2

1Department of Neurology, Bezmialem Vakif University Hospital, Turkey
2Department of Neurology, Basaksehir Cam and Sakura City Hospital, Turkey

^*Correspondance to: Saniye Karabudak 

Abstract

We report a rare case of Creutzfeldt-Jakob disease whose complaints started after a few weeks’ mRNA COVID-19 vaccine. Prion diseases are neurodegenerative diseases which have long incubation periods. After clinical symptoms appear, it progresses rapidly to death. Beside clinical symptoms, EEG, Brain MRI and Protein 14-3-3 pozitivity support to diagnose. There is no effective treatment. In this paper, we present a case admitted to our clinic with rapidly progressive cognitive impairment after mRNA COVID-19 vaccine along with protein 14.3.3 positivity.

Citation:

Karabudak S, Kurtoğlu AV, Uslu F, Gürsoy AE. A Case Report of Creutzfeldt-Jakob Disease after mRNA COVID-19 Vaccine. Ann Clin Case Rep. 2023; 8: 2408..