Sjögren Syndrome Associated Cerebral Venous Sinus Thrombosis with Presenting as Convexal Subarachnoid Hemorrhage: A Case Report

Zeqiang Ji1,2,3, Feifei Ma1,2,3, Yanru Du4, Gehong Dong4, Ruile Fang1,2,3, Wei Zhou5, Yi Ju1,2,3*, Ruijun Ji1,2,3* and Xingquan Zhao1,2,3*

1Department of Neurology, Division of Vascular Neurology, Beijing Tiantan Hospital, Capital Medical University, China 2China National Clinical Research Center for Neurological Diseases, China 3Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, China 4Department of Pathology, Beijing Tiantan Hospital, Capital Medical University, China 5Department of Rheumatology, Beijing Tiantan Hospital, Capital Medical University, China

^*Correspondance to: Ruijun Ji,Yi Ju,Xingquan Zhao 

 PDF  Full Text Case Report | Open Access

Abstract:

Cerebral Venous Sinus Thrombosis (CVST) is an uncommon cerebrovascular disease caused by cerebral venous sinus blockage, leading to increased intracranial pressure, venous infarction, or bleeding. Among the patients, convexal Subarachnoid Hemorrhage (cSAH) caused by CVST is relatively rare, accounting for only 0.5% to 0.8% [1] of all CVST patients. Convexal SAH is a subtype of non-aneurysmal SAH, characterized by the limitation of bleeding in one or several convex cortical sulci. The pathogenesis of CVST is challenging to find but valuable for subsequent treatment. We report a patient with CVST caused by primary Sjögren Syndrome (pSS) and secondary "Noncriteria" antiphospholipid syndrome, whose first manifestation was cSAH. After diagnosis, the patient was given long-term anticoagulation to treat CVST and "Non-criteria" antiphospholipid syndrome. The case aims to discuss the diagnosis, pathogenesis, personalized treatment plan, and the risk of recurrence.

Keywords:

Cerebral venous sinus thrombosis; Sjögren syndrome; Convexsal subarachnoid hemorrhage

Cite the Article:

Ji Z, Ma F, Du Y, Dong G, Fang R, Zhou W, et al. Sjögren Syndrome Associated Cerebral Venous Sinus Thrombosis with Presenting as Convexal Subarachnoid Hemorrhage: A Case Report. Ann Clin Case Rep. 2022; 7: 2174..