Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Biochemistry and Biostatistics
  •  Pneumonia
  •  ENT
  •  Ophthalmology
  •  Orthopedics & Rheumatology
  •  Cardiovascular Medicine
  •  Nuclear Medicine
  •  Forensic and Legal Medicine

Abstract

Citation: Ann Clin Case Rep. 2022;7(1):2134.DOI: 10.25107/2474-1655.2134

Soft Tissue Abscesses Related to Repeated Intramuscular or Subcutaneous Cyclizine Injections

Will Taylor1, Bethany Smart2 and Nick P Thompson1*

1Department of Gastroenterology, Freeman Hospital, England, UK 2Department of Pharmacy, Freeman Hospital, England, UK

*Correspondance to: Nick P Thompson 

 PDF  Full Text Case Report | Open Access

Abstract:

Cyclizine is an effective anti-emetic that has a variety of potential risks and side effects. These include reduced appetite, constipation, palpitations, postural hypotension and urinary retention, which are well recognized. There has been concern recently about regular intravenous use especially using central lines with extravasation and line erosion, probably due to the low pH of the preparation. We present two patients with gastroparesis and persistent nausea unresponsive to oral anti-emetics treated with long term intramuscular or subcutaneous Cyclizine. This resulted in long-term skin and subcutaneous changes and the development of significant soft tissue abscess formation, each requiring extensive surgery for drainage. Conclusion: Intramuscular or subcutaneous Cyclizine, in addition to other side effects and risks, may be associated with skin changes at the site of repeated injection and the development of abscesses. Regular intramuscular or subcutaneous Cyclizine should be avoided if possible.

Keywords:

Cite the Article:

Taylor W, Smart B, Thompson NP. Soft Tissue Abscesses Related to Repeated Intramuscular or Subcutaneous Cyclizine Injections. Ann Clin Case Rep. 2022; 7: 2134..

Search Our Journal

Journal Indexed In

Articles in PubMed

Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and Naturally Occurring Compounds, Part II
 PubMed  PMC  PDF  Full Text
Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and other Naturally Occurring Compounds, Part I
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Delayed Pericardial Tamponade after Thrombolytic and Anticoagulant Treatment for Pulmonary Embolism
 Abstract  PDF  Full Text
Reduction of the Corpus Callosum in First-Episode, Drug Naive Schizophrenia Patients is Worsened in the Absence of Depression Symptoms: Evidence for Depression-Type Schizophrenia
 PDF  Full Text
View More...