Very Late Recurrence of Hepatocellular Carcinoma after Sequential Liver and Kidney Transplant: Is There an Influence of Immunosuppression?

Renato Ferreira da Silva, Carolina Antunes Marques, Fábio Leite Couto Fernandez, Dalisio de Santi Neto, Helen C Felicio, Wiliam Jose Duca, Ida Maria M Fernandez, Paulo Cesar Arroyo Jr and Rita de Cásisa Martins Alves da Silva

Department of Surgery and Liver Transplantation, Hospital de Base/ FUNFARME of the São José do Rio Preto Medicine School / FAMERP, Brazil
Student of São José do Rio Preto Medicine School/FAMERP, Brazil
Department of Oncology, Hospital de Base/FUNFARME São José do Rio Preto, Brazil
Department of Pathology, Hospital de Base/ FUNFARME of the São José do Rio Preto Medicine School/FAMERP, Brazil
Department of Gastroenterology, Hospital de Base/ FUNFARME São José do Rio Preto, Brazil
Department of Surgery and Kidney Transplantation, Hospital de Base/ FUNFARME of the São José do Rio Preto Medicine School / FAMERP, Brazil
Department of General Surgery, Hospital de Base/ FUNFARME São José do Rio Preto, Brazil

^*Correspondance to: Renato Ferreira da Silva 

 PDF  Full Text Case Report | Open Access

Abstract:

We report a case of a very late recurrence of hepatocellular carcinoma, which occurred after kidney transplantation. Six years earlier, liver transplantation had been performed due to hepatocellular carcinoma. This is the second case reported in the medical literature where a recurrence occurred after a strong immunosuppression regimen. The influence of immunosuppression in the recurrence of hepatocellular carcinoma will be discussed in this case.

Keywords:

Liver; Kidney; Transplantation; Immunosuppression; Hepatocellular; Carcinoma; Recurrence; Mycophenolate sodium; Mycophenolate mofetil; Sirolimus and tacrolimus

Cite the Article:

da Silva RF, Marques CA, Fernandez FLC, de Santi Neto D, Felicio HC, Duca WJ, et al. Very Late Recurrence of Hepatocellular Carcinoma after Sequential Liver and Kidney Transplant: Is There an Influence of Immunosuppression?. Ann Clin Case Rep. 2017; 2: 1236.