Journal Basic Info
- Impact Factor: 1.809**
- H-Index: 6
- ISSN: 2474-1655
- DOI: 10.25107/2474-1655
Major Scope
- Dermatology and Cosmetology
- Anatomy
- Molecular Biology
- Pathology
- Child Birth
- Endocrinology
- ENT
- Orthopedics & Rheumatology
Abstract
Citation: Ann Clin Case Rep. 2016;1(1):1205.DOI: 10.25107/2474-1655.1205
Goltz-Gorlin Syndrome: Report of Two Cases
Rashid Soufizadeh and Mozhgan Kazemian
Department of Oral and Maxillofacial Surgery, Mashhad University of Medical Sciences, Iran
*Correspondance to: Rashid Soufizadeh
PDF Full Text Case Report | Open Access
Abstract:
Goltz-Gorlin syndrome or Nevoid Basal Cell Carcinoma syndrome (NBCCS) is an infrequent multisystemic disease that is inherited in a dominant autosomal pattern, which shows a high level of penetrance and variable expressiveness. The syndrome is associated with multiple Keratocystic Odontogenic Tumors (KCOT) in 90% of cases. In addition to jaw cysts, multiple basal cell carcinomas and skeletal anomalies are common findings. KCOTs associated with this syndrome can be seen in both maxilla and mandible but there is more tendencies to posterior mandible and the recurrence rate is more than nonsyndromic cases. In this article we describe two patients with diagnosis of Goltz-Gorlin syndrome, its typical findings and finally we discuss about the treatment method used for jaw cysts and the outcome of 1 year follow-up.
Keywords:
Goltz-Gorlin syndrome; Nevoid basal cell carcinoma; Keratocystic odontogenic
tumors
Cite the Article:
Soufizadeh R, Kazemian M. Goltz- Gorlin Syndrome: Report of Two Cases. Ann Clin Case Rep. 2016; 1: 1205.
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